The first time you start the Hex Editor Neo, you are asked to choose a default tool window layout.
You are offered a choice of three options: Novice user, Advanced user and Expert user.
After you click an option, Hex Editor Neo's user interface immediately switches to the selected layout. Once you have chosen your layout, press the Continue button.
Although the “Choose Default User Interface Layout” window is presented only once, you can easily change a layout at a later time. To do this, go to the View » Predefined Layouts menu, and select a layout from the list. The “Choose Default Layout” window may also be invoked using the Quick UI Tweak… button on the toolbar.