The Hex Editor Neo allows you to quickly create an empty document with a use of the File » New » New File command. Created document is virtual and is not backed up by any real file until you save it for the first time.
Empty document always has the size of zero bytes. You can use the wide range of editing commands to insert data to the file.
File » New » New Intel Hex and File » New » New Motorola S-Records commands allow you to create empty Intel Hex and Motorola S-Records encoded binary files.
Macros and scripts running in the editor may use the newDocument method to create new empty document in the editor.